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Dimethyl fumarate
72 CAD
Only 1000 item(s) left in stock.
For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.
Products Details
Product Description
– Dimethyl fumarate (DMF) is an Nrf2 activator with oral activity and blood-brain barrier permeability. Dimethyl fumarate has antimicrobial, anti-inflammatory, and immunomodulatory activities and has been used in the study of multiple sclerosis.
For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.
Web ID
– T0492
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C6H8O4
Citations
– 1. Wang Y, Ma H, Huang J, et al. Discovery of bardoxolone derivatives as novel orally active necroptosis inhibitors. European Journal of Medicinal Chemistry,. 2021 Feb 15;212:113030
2. Dai Y, Li H, Fan S, et al.Dimethyl fumarate promotes the degradation of HNF1B and suppresses the progression of clear cell renal cell carcinoma.Cell Death & Disease.2025, 16(1): 1-12.
References
– Albrecht P, et al. J Neuroinflammation,2012, 9, 163.
CAS Number
– 624-49-7
Molecular Weight
– C6H8O4
Compound Purity
– 0.9988
SMILES
– COC(=O)C=CC(=O)OC
Target
– Lipase
Pathway
– NF-κB|||Microbiology/Virology|||Autophagy|||Metabolism|||Immunology/Inflammation|||Proteases/Proteasome
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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