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Pioglitazone

SKU T0214-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 56 CAD through 563 CAD

For Research Use Only (RUO). This product is sold strictly for laboratory research use. Not for human or veterinary consumption, therapeutic, or diagnostic use.For sale to research organizations and laboratories only; not for patients or for personal use.

Size

1 mL * 10 mM (in DMSO)10 mg 100 mg 25 mg 5 mg 50 mg 500 mg

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Products Details

Product Description

– Pioglitazone (U 72107) is an insulin sensitizing agent and thiazolidinedione indicated for the treatment of type 2 diabetes, and has been linked to rare instances of acute liver injury.

For Research Use Only (RUO). This product is sold strictly for laboratory research use only. Not for human or veterinary consumption, therapeutic, or diagnostic use. Any pharmacological, therapeutic, cosmetic, or biological effects described above are provided as research context only and do not represent intended or approved uses of this product.

Web ID

– T0214

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H20N2O3S

Citations

– 1. Zhan Z T, Liu L, Cheng M Z, et al. The Effects of 6 Common Antidiabetic Drugs on Anti-PD1 Immune Checkpoint Inhibitor in Tumor Treatment. Journal of Immunology Research. 2022 2. Qi Y, Hu M, Qiu Y, et al.Mitoglitazone ameliorates renal ischemia/reperfusion injury by inhibiting ferroptosis via targeting mitoNEET.Toxicology and Applied Pharmacology.2023: 116440. 3. Schöckel L, Woischke C, Surendran S A, et al.PPARG activation promotes the proliferation of colorectal cancer cell lines and enhances the antiproliferative effect of 5-fluorouracil.BMC cancer.2024, 24(1): 1-12. 4. Huang Q, Ru Y, Luo Y, et al.Identification of a targeted ACSL4 inhibitor to treat ferroptosis-related diseases.Science Advances.2024, 10(13): eadk1200. 5. Liu W, You D, Lin J, et al.SGLT2 inhibitor promotes ketogenesis to improve MASH by suppressing CD8+ T cell activation.Cell Metabolism.2024

References

– Jaakkola T, et al. Basic Clin Pharmacol Toxicol,2006, 99(1), 44-51.

CAS Number

– 111025-46-8

Molecular Weight

– C19H20N2O3S

Compound Purity

– 0.9957

SMILES

– C(C1C(=O)NC(=O)S1)C2=CC=C(OCCC3=CC=C(CC)C=N3)C=C2

Target

– NMDAR|||GluR

Pathway

– DNA Damage/DNA Repair|||Metabolism|||Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.