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Products Details
Product Description
– ZYZ-488 is a competitive apoptotic protease activating factor-1 (Apaf-1) inhibitor. ZYZ-488 inhibits the activation of binding protein procaspase-9 and procaspase-3[1].
Web ID
– HY-100472
Storage Temperature
– 4°C (Powder, stored under nitrogen)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H29N3O11
References
– [1]Wang Y, et al. The discovery of a novel inhibitor of apoptotic protease activating factor-1 (Apaf-1) for ischemic heart: synthesis, activity and target identification. Sci Rep. 2016 Jul 22;6:29820.
CAS Number
– 1470302-79-4
Molecular Weight
– 487.46
Compound Purity
– 99.80
SMILES
– O=C(OCCCCNC(N)=N)C(C=C1OC)=CC(OC)=C1O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 200 mg/mL (ultrasonic)|H2O : ≥ 100 mg/mL
Target
– Caspase
Pathway
– Apoptosis
Product type
– Reference compound
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