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ZX-29
Price range: 149 CAD through 2,544 CAD
Products Details
Product Description
– ZX-29 is a potent and selective inhibitor of ALK with IC50 values of 2.1 nM, 1.3 nM, and 3.9 nM for ALK, ALK [L1196M], and ALK [G1202R] mutations, respectively. It also induces protective autophagy and exhibits antitumor effects.
Web ID
– T13416
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H28ClN7O3S
References
– Gou W, et al. ZX-29, a novel ALK inhibitor, induces apoptosis via ER stress in ALK rearrangement NSCLC cells and overcomes cell resistance caused by an ALK mutation. Biochim Biophys Acta Mol Cell Res. 2020 Mar 26;1867(7):118712.
CAS Number
– 2254805-62-2
Molecular Weight
– C23H28ClN7O3S
Compound Purity
– 0.9832
SMILES
– COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NS(C)(=O)=O)n1)N1CCN(C)CC1
Target
– Others
Pathway
– Tyrosine Kinase/Adaptors|||Angiogenesis
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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