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Products Details
Product Description
– Zotiraciclib (also known as TG02 and SB1317) is an innovative small-molecule compound with potent inhibitory effects on CDK, JAK2, and FLT3. By inhibiting cyclin-dependent kinase 9 (CDK9) and depleting Myc, it serves as a treatment for cancers that can penetrate the blood-brain barrier. Zotiraciclib is one of the numerous CDK inhibitors under investigation; other compounds targeting CDK9, utilized for treating acute myeloid leukemia, include alvocidib and atuveciclib. Myc overexpression is a known factor in many cancers, with 80% of glioblastomas exhibiting this characteristic.
Web ID
– T202626
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C29H32N4O8
CAS Number
– 1204918-73-9
Molecular Weight
– C29H32N4O8
SMILES
– OC(=O)CC(O)(CC(O)=O)C(O)=O.CN1CC=CCCOC2=CC(=CC=C2)C3=CC=NC(NC4=CC=CC(C1)=C4)=N3
Target
– Histone Demethylase|||PD-1/PD-L1
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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