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ZM223
SKU
HY-101790-Get quote
Category Reference compound
Tags Cancer, Metabolic Enzyme/Protease, NEDD8-activating Enzyme
Products Details
Product Description
– ZM223 is a potent non-covalent NEDD8 activating enzyme (NAE) inhibitor, orally active[1].
Web ID
– HY-101790
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C23H17F3N4O2S2
References
– [1]Ma H, et al. Discovery of benzothiazole derivatives as novel non-sulfamide NEDD8 activating enzyme inhibitors by target-based virtual screening. Eur J Med Chem. 2017 Jun 16;133:174-183.
CAS Number
– 2031177-48-5
Molecular Weight
– 502.53
SMILES
– O=C(C1=CC=C(C(F)(F)F)C=C1)NC2=NC3=CC=C(NC(CSC4=CC=C(N)C=C4)=O)C=C3S2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 83.33 mg/mL (ultrasonic)
Target
– NEDD8-activating Enzyme
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.