(Z)-4EGI-1
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(Z)-4EGI-1

SKU T37099-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 190 CAD through 1,904 CAD

Products Details

Product Description

– (Z)-4EGI-1, the Z-isomer of 4EGI-1, serves as an inhibitor of both the eIF4E/eIF4G interaction and translation initiation. It effectively binds to eIF4E, exhibiting an IC50 of 43.5 μM and a Kd value of 8.74 μM. Notably, (Z)-4EGI-1 possesses anticancer activity[1][2].

Web ID

– T37099

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H12Cl2N4O4S

References

– Khuloud Takrouri, et al. Structure-activity Relationship Study of 4EGI-1, Small Molecule eIF4E/eIF4G Protein-Protein Interaction Inhibitors. Eur J Med Chem. 2014 Apr 22;77:361-77.

CAS Number

– 901787-88-0

Molecular Weight

– C18H12Cl2N4O4S

SMILES

– N(/N=C(/CC1=C(N(=O)=O)C=CC=C1)C(O)=O)C2=NC(=CS2)C3=CC(Cl)=C(Cl)C=C3

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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