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XRK3F2
Price range: 54 CAD through 894 CAD
Products Details
Product Description
– XRK3F2 is an inhibitor of the p62-ZZ domain, blunts MM-induced Runx2 suppression in vitro, and induces new bone formation and remodeling in the presence of tumor in vivo.
Web ID
– T13360
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C23H24ClF2NO3
Citations
– 1. Xu Y, Zhu C, Zhu C, et al.SQSTM1/p62 promotes the progression of gastric cancer through epithelial-mesenchymal transition.Heliyon.2024
References
– Adamik J, et al. XRK3F2 Inhibition of p62-ZZ Domain Signaling Rescues Myeloma-Induced GFI1-Driven Epigenetic Repression of the Runx2 Gene in Pre-osteoblasts to Overcome Differentiation Suppression. Front Endocrinol (Lausanne). 2018 Jun 29;9:344.
CAS Number
– 2375193-43-2
Molecular Weight
– C23H24ClF2NO3
Compound Purity
– 0.9891
SMILES
– Cl.OCCNCc1ccc(OCc2ccc(F)cc2)c(OCc2ccc(F)cc2)c1
Target
– PI3K|||Autophagy|||ATM/ATR|||DNA-PK|||mTOR
Pathway
– Autophagy
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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