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VU591 hydrochloride
SKU
HY-108585-10mM/1mL
Category Reference compound
Tags Membrane Transporter/Ion Channel, Neurological Disease, Potassium Channel
$450 – $495
Products Details
Product Description
– VU591 hydrochloride is a potent, selective renal outer medullary potassium channel (ROMK or Kir1.1) inhibitor, with an IC50 of 0.24 μM. VU591 hydrochloride can be used for neurological research with HY-108585A (the equivalent of VU591 hydrochloride)[1].
Web ID
– HY-108585
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Molecular Formula
– C16H13ClN6O5
References
– [1]Masayoshi Okada, et al. Antidepressive effect of an inward rectifier K+ channel blocker peptide, tertiapin-RQ. PLoS One. 2020 Nov 13;15(11):e0233815.|[2]Bhave G, et al. Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel. Mol Pharmacol. 2011 Jan;79(1):42-50.
CAS Number
– 1315380-70-1
Molecular Weight
– 404.76
Compound Purity
– 99.0
SMILES
– O=[N+](C1=CC=C2N=C(COCC3=NC4=CC=C([N+]([O-])=O)C=C4N3)NC2=C1)[O-].[H]Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 16.67 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Potassium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.