VU591 hydrochloride

SKU T13320-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 1,237 CAD

Products Details

Product Description

– VU591 hydrochloride is a selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50:0.24 μM). Thought to block the intracellular pore of the Kir1.1 channel. Exhibits no effect on Kir7.1 at concentrations up to 10 μM; does not inhibit Kir2.1, Kir2.3 or Kir4.1. Displays similar potency to VU 590

Web ID

– T13320

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H13ClN6O5

References

– Bhave G, et al. Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel. Mol Pharmacol. 2011 Jan;79(1):42-50.

CAS Number

– 1315380-70-1

Molecular Weight

– C16H13ClN6O5

Compound Purity

– 0.9922

SMILES

– Cl.[O-][N+](=O)c1ccc2nc(COCc3nc4ccc(cc4[nH]3)[N+]([O-])=O)[nH]c2c1

Target

– 5-HT Receptor|||AChR

Pathway

– Membrane transporter/Ion channel

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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