VU0422288
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VU0422288

SKU T29135-5 mg Category Brand:

Price range: 117 CAD through 2,128 CAD

Products Details

Product Description

– VU0422288 (ML396) is a potent orthosteric modulator of type III mGlu receptors (mGlus).VU0422288 shows inhibition of mGluR4, mGluR7, and mGluR8 in a calcium mobilization assay.VU0422288 can be used to study Rett syndrome (RTT).

Web ID

– T29135

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H11Cl2N3O2

References

– Gogliotti RG, et al. mGlu7 potentiation rescues cognitive, social, and respiratory phenotypes in a mouse model of Rett syndrome. Sci Transl Med. 2017 Aug 16;9(403):eaai7459.

CAS Number

– 1630936-95-6

Molecular Weight

– C17H11Cl2N3O2

Compound Purity

– 0.9548

SMILES

– Clc1ccc(Oc2ccc(NC(=O)c3ccccn3)cc2Cl)nc1

Pathway

– Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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