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VU-29
Price range: 46 CAD through 942 CAD
Products Details
Product Description
– VU-29 is a positive allosteric mGlu5 receptor modulator with an EC50 of 9 nM and a Ki of 244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes [EC50: rmGluR1/rmGluR2=557 nM/1.5 μM; hmGluR4=154 nM].
Web ID
– T23515
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H16N4O3
References
– Chen Y , Nong Y , Goudet C , et al. Interaction of novel positive allosteric modulators of metabotropic glutamate receptor 5 with the negative allosteric antagonist site is required for potentiation of receptor responses.[J]. Molecular Pharmacology, 2007, 71(5):1389-1398.
CAS Number
– 890764-36-0
Molecular Weight
– C22H16N4O3
Compound Purity
– 0.9963
SMILES
– N(C(=O)C1=CC=C(N(=O)=O)C=C1)C=2N(N=C(C2)C3=CC=CC=C3)C4=CC=CC=C4
Pathway
– Neuroscience
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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