VER-155008
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VER-155008

SKU T7010-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 62 CAD through 1,101 CAD

Products Details

Product Description

– VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively, >100-fold selectivity over HSP90.

Web ID

– T7010

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H23Cl2N7O4

Citations

– 1. Du Y, Chen Z, Yan P, et al. Arginine–Arginine–Leucine Peptide Targeting Heat Shock Protein 70 for Cancer Imaging. Molecular Pharmaceutics. 2021 2. Wang J, Zhang J, Guo Z, et al.Targeting HSP70 chaperones by rhein sensitizes liver cancer to artemisinin derivatives.Phytomedicine.2023: 155156. 3. Yang X, Zhao X, Zhao Z, et al.Genome-wide analysis reveals transcriptional and translational changes during diapause of the Asian corn borer (Ostrinia furnacalis).BMC biology.2024, 22(1): 1-23.

References

– Massey AJ, et al. Cancer Chemother Pharmacol. 2010, 66(3), 535-545.

CAS Number

– 1134156-31-2

Molecular Weight

– C25H23Cl2N7O4

Compound Purity

– 0.9953

SMILES

– Nc1ncnc2n([C@@H]3O[C@H](COCc4ccc(cc4)C#N)[C@@H](O)[C@H]3O)c(NCc3ccc(Cl)c(Cl)c3)nc12

Pathway

– Cytoskeletal Signaling|||Autophagy|||GPCR/G Protein|||Endocrinology/Hormones|||Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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