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Products Details
Product Description
– VD2173 is a side chain cyclized macrocyclic peptide inhibitor of HGF-activating serine proteases. VD2173 potently inhibits matriptase and hepsin. VD2173 can be used for the research of lung cancer[1].
Web ID
– HY-145263
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C31H45N9O6S
References
– [1]Damalanka VC, et, al. Macrocyclic Inhibitors of HGF-Activating Serine Proteases Overcome Resistance to Receptor Tyrosine Kinase Inhibitors and Block Lung Cancer Progression. J Med Chem. 2021 Dec 23;64(24):18158-18174.
CAS Number
– 2574389-19-6
Molecular Weight
– 671.81
SMILES
– O=C1N[C@H](C(N[C@H](C(C2=NC3=CC=CC=C3S2)=O)CCCNC(N)=N)=O)CCCCNC(C[C@H](NC(C)=O)C(N[C@H]1CC(C)C)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ser/Thr Protease
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
