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USL311
$250 – $1,350
Products Details
Product Description
– USL311 is a potent and selective CXCR4 antagonist, with anti-tumor activity. USL311 prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4[1].
Web ID
– HY-114244
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H34N6O
References
– [1]Peter Richardson. Usl-311 for use in the treatment of cancer. WO2018162924A1|[2]Takacs GP, et al. Modulation of the chemokine/chemokine receptor axis as a novel approach for glioma therapy. Pharmacol Ther. 2021 Jun;222:107790.
CAS Number
– 1373268-67-7
Molecular Weight
– 422.57
Compound Purity
– 99.97
SMILES
– O=C(C1=NC(N2CCN(C3CCN(C(C)C)CC3)CCC2)=CC=C1)NC4=CC=NC=C4
Clinical Information
– Phase 2
Research Area
– Cancer; Endocrinology
Solubility
– DMSO : 18.57 mg/mL (ultrasonic;warming;heat to 80°C)
Target
– CXCR
Isoform
– CXCR4
Pathway
– GPCR/G Protein;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
