Download Files:
Products Details
Product Description
– UIAA-II-232 (compound 19b) is a potent DNA gyrase catalytic inhibitor with an IC50 value of 3.5 µM[1].
Web ID
– HY-147729
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C20H24FN5O3
References
– [1]Aguirre AL, et al. Identification of an ethyl 5,6-dihydropyrazolo[1,5-c]quinazoline-1-carboxylate as a catalytic inhibitor of DNA gyrase. Bioorg Med Chem. 2020 May 15;28(10):115439.
CAS Number
– 2428407-03-6
Molecular Weight
– 401.43
SMILES
– O=C(C1=C2N(N=C1)C(N(CC)C3=C2C=C(F)C(N4C[C@H](CN)CC4)=C3)=O)OCC
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
