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Tolimidone
$55 – $460
Products Details
Product Description
– Tolimidone is a potent and selective allosteric activator of Lyn kinase with an EC50 of 63 nM.
Web ID
– HY-59047
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C11H10N2O2
References
– [1]Saporito MS, et al. MLR-1023 is a potent and selective allosteric activator of Lyn kinase in vitro that improves glucose tolerance in vivo. J Pharmacol Exp Ther. 2012 Jul;342(1):15-22.|[2]Ochman AR, et al. The Lyn kinase activator MLR-1023 is a novel insulin receptor potentiator that elicits a rapid-onset and durable improvement in glucose homeostasis in animal models of type 2 diabetes. J Pharmacol Exp Ther. 2012 Jul;342(1):23-32.
CAS Number
– 41964-07-2
Molecular Weight
– 202.21
Compound Purity
– 99.89
SMILES
– O=C1N=CC(OC2=CC=CC(C)=C2)=CN1
Clinical Information
– Phase 2
Research Area
– Metabolic Disease
Solubility
– DMSO : 150 mg/mL (ultrasonic)
Target
– Src
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
