Tocainide (hydrochloride)

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Products Details

Product Description

– Tocainide hydrochloride is a sodium channel blocker, it blocks the sodium channels in the pain-producing foci in the nerve membranes. Tocainide hydrochloride is a primary amine analog of lidocaine, can be used for the treatment of tinnitus[1][2].

Web ID

– HY-B1798A

Storage Temperature

– 4°C (Powder, stored under nitrogen)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C11H17ClN2O

References

– [1]De Luca A,et al.Optimal requirements for high affinity and use-dependent block of skeletal muscle sodium channel by N-benzyl analogs of tocainide-like compounds.Mol Pharmacol. 2003 Oct;64(4):932-45.|[2]Alpert JS, et al. Chemistry, pharmacology, antiarrhythmic efficacy and adverse effects of tocainide hydrochloride, an orally active structural analog of lidocaine. Pharmacotherapy. 1983 Nov-Dec;3(6):316-23.

CAS Number

– 71395-14-7

Molecular Weight

– 228.72

Compound Purity

– 99.49

SMILES

– CC(N)C(NC1=C(C)C=CC=C1C)=O.[H]Cl

Clinical Information

– Launched

Research Area

– Inflammation/Immunology

Solubility

– DMSO : 125 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)

Target

– Sodium Channel

Pathway

– Membrane Transporter/Ion Channel

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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