Download Files:
Products Details
Product Description
– TLR4 agonist-1 (compound 17a) is a potent agonist of Toll-like Receptor 4 (TLR4), and induces the generation of MIP-1β in RAW 264.7 and MM6 cells[1].
Web ID
– HY-149650
Shipping
– Room temperature
Molecular Formula
– C81H158N3O15P
References
– [1]Khalaf JK, et al. Diamino Allose Phosphates: Novel, Potent, and Highly Stable Toll-like Receptor 4 Agonists. J Med Chem. 2023;66(20):13900-13917.
CAS Number
– 2374139-51-0
Molecular Weight
– 1445.11
SMILES
– OC[C@H]1O[C@@H](OC[C@@H](C(O)=O)NC(C[C@H](OCCCCCCCCCC)CCCCCCCCCCC)=O)[C@H](NC(C[C@H](OCCCCCCCCCC)CCCCCCCCCCC)=O)[C@H](NC(C[C@H](OCCCCCCCCCC)CCCCCCCCCCC)=O)[C@@H]1OP(O)(O)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Toll-like Receptor (TLR)
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
