Thiostrepton

SKU T1679-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 88 CAD

Products Details

Product Description

– Thiostrepton (Alaninamide) is a one of the CYCLIC PEPTIDES from Streptomyces that is active against gram-positive bacteria. In veterinary medicine, it has been used in mastitis caused by gram-negative organisms and in dermatologic disorders.

Web ID

– T1679

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C72H85N19O18S5

Citations

– 1. Zhou Z, Chen H, Xie R, et al. Epigenetically modulated FOXM 1 suppresses dendritic cell maturation in pancreatic cancer and colon cancer. Molecular Oncology. 2019, 13(4): 873-893 2. Lai W, Zhu W, Li X, et al. GTSE1 promotes prostate cancer cell proliferation via the SP1/FOXM1 signaling pathway. Laboratory Investigation. 2021 May;101(5):554-563.

References

– Kuiper EG, Conn GL. J Biol Chem. 2014 Sep 19;289(38):26189-200.

CAS Number

– 1393-48-2

Molecular Weight

– C72H85N19O18S5

Compound Purity

– 0.9895

SMILES

– CC[C@H](C)[C@@H]1N[C@@H]2C=Cc3c(cc(nc3[C@H]2O)C(=O)O[C@H](C)[C@@H]2NC(=O)c3csc(n3)[C@@H](NC(=O)[C@H]3CSC(=N3)C(NC(=O)[C@@H](NC(=O)c3csc(n3)[C@]3(CCC(=N[C@@H]3c3csc2n3)c2nc(cs2)C(=O)NC(=C)C(=O)NC(=C)C(N)=O)NC(=O)[C@H](C)NC(=O)C(=C)NC(=O)[C@H](C)NC1=O)[C@@H](C)O)=CC)C(C)(O)[C@@H](C)O)[C@H](C)O

Target

– Others

Pathway

– Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Microbiology/Virology

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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