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Products Details
Product Description
– TH1217, a potent and selective inhibitor of dCTPase pyrophosphatase 1 (dCTPase), demonstrates an IC50 value of 47 nM. It amplifies the cytotoxic impact of cytidine analogues on leukemia cells and exhibits potential against COVID-19 by modulating SARS-CoV-2 interactors.
Web ID
– T38271
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H17BCl2N4O6
References
– Llona-Minguez et al (2016) Discovery of the first potent and selective inhibitors of human dCTP pyrophosphatase 1. J.Med.Chem. 59 1140
CAS Number
– 1862212-48-3
Molecular Weight
– C20H17BCl2N4O6
Compound Purity
– 0.993
SMILES
– Cc1nc2c(c(Cl)c(Cl)cc2n1Cc1ccc(cc1)[B-]12OC(=O)C[N+]1(C)CC(=O)O2)[N+]([O-])=O
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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