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Tetrahydrocoptisine
Price range: 70 CAD through 917 CAD
Products Details
Product Description
– 1. Tetrahydrocoptisine (STYLOPINE) has effective effects in suppressing inflammation. 2. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibiting of NF-κB signaling pathways, which may involve the inhibition of pulmonary inflammatory process. 3. Tetrahydrocoptisine has gastroprotective activity, is attributed to reducing NO production and adjusting the pro-inflammatory cytokine, inhibited neutrophil accumulation and NF-κB expression. 4. Tetrahydrocoptisine is an active anti-inflammatory constituent by inhibition of TNF-α, IL-6 and NO production possibly via down-regulation of NF-κB activation, phospho-ERK1/2 and phospho-p38MAPK signal pathways.
Web ID
– T4S2063
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H17NO4
References
– Li W , Huang H , Niu X , et al. Tetrahydrocoptisine Protects Rats from LPS-Induced Acute Lung Injury[J]. Inflammation, 2014, 37(6):2106-2115.
CAS Number
– 4312-32-7
Molecular Weight
– C19H17NO4
Compound Purity
– 0.9971
SMILES
– C1Oc2cc3CCN4Cc5c6OCOc6ccc5CC4c3cc2O1
Pathway
– MAPK|||NF-κB
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
