Tetrac

SKU T36715-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 62 CAD through 701 CAD

Products Details

Product Description

– Tetrac (Tetraiodothyroacetic acid) is a derivative of L-thyroxine (T4), a thyroxine integrin receptor antagonist.Tetrac induces antiproliferation by blocking EGFR-mediated cell signaling in colorectal cancer cells.Tetrac blocks the effects of T4 and 3,5,3′-triiodo-L-thyronine (T3) on the cell-surface thyroxine integrin αvβ3 receptors.Tetra has anti-angiogenic, anti-tumor activity and pro-apoptotic activity.

Web ID

– T36715

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C14H8I4O4

References

– Schmohl KA, et al. Tetrac as an anti-angiogenic agent in cancer. Endocr Relat Cancer. 2019;26(6):R287-R304.

CAS Number

– 67-30-1

Molecular Weight

– C14H8I4O4

Compound Purity

– 0.9904

SMILES

– OC(=O)Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1

Pathway

– Angiogenesis|||JAK/STAT signaling|||Apoptosis|||Tyrosine Kinase/Adaptors

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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