SX-517

SKU T28893-25 mg Category Brand:

Price range: 1,824 CAD through 3,792 CAD

Products Details

Product Description

– SX-517 is a potent noncompetitive boronic acid CXCR1/2 antagonist. SX-517 inhibits CXCL1-induced Ca(2+) flux (IC50 = 38 nM) in human PMNs.

Web ID

– T28893

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H16BFN2O3S

References

– Schuler AD, Engles CA, Maeda DY, Quinn MT, Kirpotina LN, Wicomb WN, Mason SN, Auten RL, Zebala JA. Boronic acid-containing aminopyridine- and aminopyrimidinecarboxamide CXCR1/2 antagonists: Optimization of aqueous solubility and oral bioavailability. Bioorg Med Chem Lett. 2015 Sep 15;25(18):3793-7. doi: 10.1016/j.bmcl.2015.07.090. Epub 2015 Jul 30. PubMed PMID: 26248802; PubMed Central PMCID: PMC4564001.

CAS Number

– 1240494-13-6

Molecular Weight

– C19H16BFN2O3S

SMILES

– C(SC1=CC=C(C(NC2=CC=C(F)C=C2)=O)C=N1)C3=C(B(O)O)C=CC=C3

Pathway

– Others

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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