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Sucralfate
SKU
HY-B0644-100 mg
Category Reference compound
Tags Anti-infection, Bacterial, Infection; Inflammation/Immunology; Cancer
$30 – $50
Products Details
Product Description
– Sucralfate (Sucrose octasulfate-aluminum complex) is a potent and orally active gastroprotectant with no systemic effects. Sucralfate inhibits peptic activity and binds to negatively charged subepithelial proteins exposed during mucosal injury, forming a viscous layer that protects the vascular bed and proliferative zone. Sucralfate is used for prevention and research of several gastrointestinal diseases in vivo[1][2].
Web ID
– HY-B0644
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C12H14Al16O75S8
References
– [1]Chaim FM, et al. Evaluation of the application of enemas containing sucralfate in tissue content of neutral and acid mucins in experimental model of diversion colitis. Acta Cir Bras. 2014 Sep;29(9):544-52.|[2]Tracy L Hill, et al. Effect of sucralfate on gastric permeability in an ex vivo model of stress-related mucosal disease in dogs. J Vet Intern Med. 2018 Mar;32(2):670-678.
CAS Number
– 54182-58-0
Molecular Weight
– 2046.42
SMILES
– [OSO3[Al2(OH5)]][C@H]([C@@H](C[OSO3[Al2(OH5)]])O1)[C@H](O[S]=O=O=O=[OH5]#[Al]#[Al])[C@]1(C[OSO3[Al2(OH5)]])O[C@@H]2[C@H](O[S]=O=O=O=[OH5]#[Al]#[Al])[C@H](O[S]=O=O=O=[OH5]#[Al]#[Al])[C@H](O[S]=O=O=O=[OH5]#[Al]#[Al])[C@@H](C[OSO3[Al2(OH5)]])O2
Clinical Information
– Launched
Research Area
– Infection; Inflammation/Immunology; Cancer
Solubility
– 1M NaOH : 20 mg/mL (ultrasonic;adjust pH to 12 with 1M NaOH)|DMSO : < 1 mg/mL|H2O : < 0.1 mg/mL
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.