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Products Details
Product Description
– STING modulator-5 (compound 38) is a STING modulator with a pIC50 value of 9.5. STING modulator-5 antagonizes peripheral blood mononuclear cells (PBMC) with a pIC50 value of 8.1. STING modulator-5 is a antagonist of THP-1 cells, it can be used for immunological disease research[1].
Web ID
– HY-148643
Shipping
– Room temperature
Molecular Formula
– C43H45F4N11O5
References
– [1]Fosbenner, David T, et al. Modulators of stimulator of interferon genes. WO 2019/069270 Al. 2022.
CAS Number
– 2305940-22-9
Molecular Weight
– 871.88
SMILES
– CN(/C1=NC(C2=CC(C)=NN2CC)=O)C3=CC=CC=C3N1CC(F)(F)C(F)(F)CN4C5=C(OCC6=CC=C(C=C6)OC)C=C(C(N)=O)C=C5N(/C4=NC(C7=CC(C)=NN7CC)=O)C
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– STING
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
