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Stearoyl-L-carnitine (chloride)
SKU
HY-130466-10 mg
Category Reference compound
Tags Endogenous Metabolite;GlyT, Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling, Metabolic Disease
$50 – $400
Products Details
Product Description
– Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM[1][2].
Web ID
– HY-130466
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C25H50ClNO4
References
– [1]Cristofano A, et, al. Serum Levels of Acyl-Carnitines along the Continuum from Normal to Alzheimer’s Dementia. PLoS One. 2016 May 19;11(5):e0155694.|[2]Carland JE, et, al. Oleoyl-L-carnitine inhibits glycine transport by GlyT2. Br J Pharmacol. 2013 Feb;168(4):891-902.|[3]Huang W, et, al. Carnitine transport and its inhibition by sulfonylureas in human kidney proximal tubular epithelial cells. Biochem Pharmacol. 1999 Oct 15;58(8):1361-70.
CAS Number
– 32350-57-5
Molecular Weight
– 464.12
Compound Purity
– 99.0
SMILES
– CCCCCCCCCCCCCCCCCC(O[C@@H](C[N+](C)(C)C)CC(O)=O)=O.[Cl-]
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite;GlyT
Isoform
– GlyT2
Pathway
– Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.