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SRS11-92

$52$1,045

Products Details

Product Description

– SRS11-92, a Ferrostatin-1 (Fer-1) analogue, is a potent ferroptosis inhibitor. SRS11-92 inhibits ferroptotic cell death induced by Erastin in HT-1080 human fibrosarcoma cells (EC50=6 nM)[1].

Web ID

– HY-116087

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C22H28N2O2

References

– [1]Skouta R, et al. Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models. J Am Chem Soc. 2014;136(12):4551-4556.|[2]Cotticelli MG, et al. Ferroptosis as a Novel Therapeutic Target for Friedreich’s Ataxia. J Pharmacol Exp Ther. 2019;369(1):47-54.

CAS Number

– 1467047-25-1

Molecular Weight

– 352.47

Compound Purity

– 98.09

SMILES

– O=C(C1=CC=C(NC2CCCCC2)C(NCC3=CC=CC=C3)=C1)OCC

Clinical Information

– No Development Reported

Research Area

– Cancer; Neurological Disease

Solubility

– DMSO : 250 mg/mL (ultrasonic)

Target

– Ferroptosis

Pathway

– Apoptosis

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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