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SRS11-92
$52 – $1,045
Products Details
Product Description
– SRS11-92, a Ferrostatin-1 (Fer-1) analogue, is a potent ferroptosis inhibitor. SRS11-92 inhibits ferroptotic cell death induced by Erastin in HT-1080 human fibrosarcoma cells (EC50=6 nM)[1].
Web ID
– HY-116087
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C22H28N2O2
References
– [1]Skouta R, et al. Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models. J Am Chem Soc. 2014;136(12):4551-4556.|[2]Cotticelli MG, et al. Ferroptosis as a Novel Therapeutic Target for Friedreich’s Ataxia. J Pharmacol Exp Ther. 2019;369(1):47-54.
CAS Number
– 1467047-25-1
Molecular Weight
– 352.47
Compound Purity
– 98.09
SMILES
– O=C(C1=CC=C(NC2CCCCC2)C(NCC3=CC=CC=C3)=C1)OCC
Clinical Information
– No Development Reported
Research Area
– Cancer; Neurological Disease
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Ferroptosis
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
