(S,R,S)-AHPC-O-Ph-PEG1-NH2

SKU T18673-2 mg Category PROTAC Brand: TargetMol

Price range: 440 CAD through 1,085 CAD

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Product Description

– (S,R,S)-AHPC-O-Ph-PEG1-NH2 (VH032-O-Ph-PEG1-NH2) is an E3 ligase ligand-linker conjugate that combines a VHL ligand for the E3 ubiquitin ligase with a PROTAC linker; it is used in PROTAC EED degrader-1, targeting EED with a potency (pKD) of 9.02[1].

Web ID

– T18673

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C32H41N5O6S

References

– Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9.

CAS Number

– 2361117-24-8

Molecular Weight

– C32H41N5O6S

SMILES

– Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COc2ccc(OCCN)cc2)C(C)(C)C)cc1

Target

– Others

Pathway

– Others

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

(S,R,S)-AHPC-O-Ph-PEG1-NH2

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