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SPR inhibitor 3
Price range: 107 CAD through 280 CAD
Products Details
Product Description
– SPR inhibitor 3 is an effective sepiapterin reductase inhibitor. SPR inhibitor 3 decreases neuropathic and inflammatory pain through a reduction of BH4 levels. SPR inhibitor 3 shows a high binding affinity to human SPR in a cell-free assay (IC50=74 nM) and efficiently reduces biopterin levels in a cell-based assay (IC50=5.2 μM).
Web ID
– T16924
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C14H18N2O3
References
– Latremoliere A, et al. Reduction of Neuropathic and Inflammatory Pain through Inhibition of the Tetrahydrobiopterin Pathway. Neuron. 2015 Jun 17;86(6):1393-406.
CAS Number
– 1292285-54-1
Molecular Weight
– C14H18N2O3
SMILES
– COCC(=O)NCCc1c(C)[nH]c2ccc(O)cc12
Target
– Cytochromes P450
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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