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Products Details
Product Description
– SPC 839 (compound 10) is an orally active inhibitor of AP-1 and NF-kB mediated transcriptional activation with IC50 of 0.008 μM[1].
Web ID
– HY-10072
Shipping
– Room temperature
Molecular Formula
– C18H14N4O3S
References
– [1]Moorthy S S Palanki, et al. The design and synthesis of novel orally active inhibitors of AP-1 and NF-kappaB mediated transcriptional activation. SAR of in vitro and in vivo studies. Bioorg Med Chem Lett. 2003 Nov 17;13(22):4077-80.
CAS Number
– 219773-55-4
Molecular Weight
– 366.39
SMILES
– O=C(C(C)=C1)N(NC2=C(C(OC)=CC=C3)C3=NC(C4=CC=CS4)=N2)C1=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– AP-1;NF-κB
Pathway
– Immunology/Inflammation;NF-κB
Product type
– Reference compound
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