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Products Details
Product Description
– SKF1 is a FK506 suppressor, causes a mitochondrially induced death in low salt, concomitant with the release of reactive oxygen species (ROS)[1].
Web ID
– HY-123454
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C23H37ClN2O2
References
– [1]Rebecca A Butcher, et al. A small molecule suppressor of FK506 that targets the mitochondria and modulates ionic balance in Saccharomyces cerevisiae. Chem Biol. 2003 Jun;10(6):521-31.
CAS Number
– 678997-25-6
Molecular Weight
– 409.01
SMILES
– O=C(OCC1CCCCC1)C2=CC=C(C(NCCCCCCCC)=N)C=C2.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– FKBP;Reactive Oxygen Species
Pathway
– Apoptosis;Autophagy;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
