Sivelestat sodium tetrahydrate

SKU T20762-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 64 CAD through 496 CAD

Products Details

Product Description

– Sivelestat sodium tetrahydrate (ONO5046 sodium tetrahydrate) is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium tetrahydrate has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19.

Web ID

– T20762

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H29N2NaO11S

References

– Kawabata K, et al. ONO-5046, a novel inhibitor of human neutrophil elastase. Biochem Biophys Res Commun. 1991 Jun 14;177(2):814-20.

CAS Number

– 201677-61-4

Molecular Weight

– C20H29N2NaO11S

Compound Purity

– 0.9964

SMILES

– O.O.O.O.[NaH].CC(C)(C)C(=O)Oc1ccc(cc1)S(=O)(=O)Nc1ccccc1C(=O)NCC(O)=O

Target

– Others

Pathway

– Proteases/Proteasome

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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