SIRT-IN-3

$32$55

Products Details

Product Description

– SIRT-IN-3 is a potent SIRT inhibitor, with an IC50 of 17 μM for SIRT1. SIRT-IN-3 shows about 4-fold and 14-fold selectivity for SIRT1 over SIRT2 and SIRT3, respectively (IC50 of 74 μM and 235 μM for SIRT2 and SIRT3, respectively)[1].

Web ID

– HY-133998

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– COVID-19-anti-virus

Molecular Formula

– C13H12N2O

References

– [1]Suzuki T, et al. 2-Anilinobenzamides as SIRT inhibitors. ChemMedChem. 2006 Oct;1(10):1059-62.

CAS Number

– 1211-19-4

Molecular Weight

– 212.25

Compound Purity

– 99.12

SMILES

– O=C(N)C1=CC=CC=C1NC2=CC=CC=C2

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 250 mg/mL (ultrasonic)

Target

– Sirtuin

Pathway

– Cell Cycle/DNA Damage;Epigenetics

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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