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Products Details
Product Description
– SIMR3030 is a potent SARS-CoV-2 PLpro inhibitor with an IC50 value of 0.0399 µg/mL. SIMR3030 shows antiviral activity. SIMR3030 decreases SARS-CoV spike, ORF1b, IFN-α, IL-6 mRNA expression. SIMR3030 exhibits a satisfactory safety profile in mice[1].
Web ID
– HY-149940
Shipping
– Room temperature
Molecular Formula
– C27H29N3O2
References
– [1]Hersi F, et al. Discovery of novel papain-like protease inhibitors for potential treatment of COVID-19. Eur J Med Chem. 2023 Jun 5;254:115380.
CAS Number
– 2708270-99-7
Molecular Weight
– 427.54
SMILES
– [H][C@@]12CC[C@]3(CC4=C(NC5=C4C=C(C=C5)OC)C[C@]3(N1CCC6=C2NC7=CC=CC=C76)[H])OC
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– SARS-CoV
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
