Silver sulfadiazine

$30

Only 1000 item(s) left in stock.

Products Details

Product Description

– Silver sulfadiazine (AgSD), a sulfonamide antibiotic, effects a dual inhibitory action on bacterial growth by its sulfa moiety (SD-SDZ) that prevents bacterial folate absorption and subsequent DNA synthesis. The silver that is released from Silver sulfadiazine binds and disrupts the DNA structure, precluding bacterial DNA replication[1].

Web ID

– HY-B1497

Storage Temperature

– 4°C (Powder, stored under nitrogen)

Shipping

– Room Temperature

Applications

– COVID-19-anti-virus

Molecular Formula

– C10H9AgN4O2S

References

– [1]Munhoz DR, et al. Alginate films functionalized with silver sulfadiazine-loaded [Mg-Al] layered double hydroxide as antimicrobial wound dressing. Int J Biol Macromol. 2019;141:504-510.|[2]Strydom SJ, et al. Poly(amidoamine) dendrimer-mediated synthesis and stabilization of silver sulfonamide nanoparticles with increased antibacterial activity. Nanomedicine. 2013;9(1):85-93.

CAS Number

– 22199-08-2

Molecular Weight

– 357.14

Compound Purity

– 98.0

SMILES

– NC(C=C1)=CC=C1S2(=O[Ag+][N]3=CC=C[N-]C3=N2)=O

Clinical Information

– Launched

Research Area

– Infection

Solubility

– DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 1 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– Antibiotic;Bacterial;DNA/RNA Synthesis

Pathway

– Anti-infection;Cell Cycle/DNA Damage

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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