SI-113
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SI-113

SKU T9589-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 61 CAD through 922 CAD

Products Details

Product Description

– SI-113 is a potent and selective inhibitor of SGK1, a serine/threonine protein kinase, that modulates several oncogenic signaling cascades.

Web ID

– T9589

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C23H24N6O

Citations

– 1. Xiong Y, Li C, Yu J, et al.A novel trifluoromethyl quinoline derivative targeting SGK1 inducing autophagy and apoptosis via regulating mTOR/FOXO3a pathway in glioblastoma.Arabian Journal of Chemistry.2024: 105909.

References

– Matteoni S, et al. The kinase inhibitor SI113 induces autophagy and synergizes with quinacrine in hindering the growth of human glioblastoma multiforme cells. J Exp Clin Cancer Res. 2019 May 17;38(1):202.

CAS Number

– 1392816-46-4

Molecular Weight

– C23H24N6O

Compound Purity

– 0.9881

SMILES

– C(=CC1=CC=CC=C1)N2C=3C(=C(NCCC4=CC=CC=C4)N=C(NCCO)N3)C=N2

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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