Seltorexant
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Seltorexant

SKU T12877L-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 50 CAD through 1,461 CAD

Products Details

Product Description

– Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain. Seltorexant is a high-affinity and selective orexin-2 receptor antagonist (pKi: 8.0 and 8.1 for human and rat OX2R).

Web ID

– T12877L

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H22FN7O

References

– Bonaventure P, et al. Characterization of JNJ-42847922, a Selective Orexin-2 Receptor Antagonist, as a Clinical Candidate for the Treatment of Insomnia. J Pharmacol Exp Ther. 2015 Sep;354(3):471-82.

CAS Number

– 1293281-49-8

Molecular Weight

– C21H22FN7O

Compound Purity

– 0.9986

SMILES

– Cc1cc(C)nc(n1)N1CC2CN(CC2C1)C(=O)c1c(F)cccc1-n1nccn1

Target

– Others

Pathway

– GPCR/G Protein|||Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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