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Ruboxistaurin hydrochloride
Price range: 104 CAD through 3,488 CAD
Products Details
Product Description
– Ruboxistaurin hydrochloride (LY 333531 hydrochloride) is an Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKCβI and PKCβII (IC50 values are 4.7 and 5.9 nM respectively). Selective for PKCβ over other PKC isozymes (IC50values are 0.052, 0.25, 0.30, 0.36, 0.60 and >100 μM for PKCη, -δ, -γ, -α, -ε and -ζ respectively). Exhibits selectivity for PKC over other ATP-dependent kinases, including protein kinase A, casein kinase and src).
Web ID
– T3689
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C28H28N4O3·HCl
References
– Jirousek MR, et al. J Med Chem. 1996, 39(14):2664-71.
CAS Number
– 169939-93-9
Molecular Weight
– C28H28N4O3·HCl
Compound Purity
– 0.9922
SMILES
– Cl.CN(C)CC1CCn2cc(C3=C(C(=O)NC3=O)c3cn(CCO1)c1ccccc31)c1ccccc21
Pathway
– Chromatin/Epigenetic|||Cytoskeletal Signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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