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Products Details
Product Description
– RORγt modulator 5 is a RORγt modulator with a Ki value of <100 nM. RORγt modulator 5 has the potential for inflammatory, metabolic, autoimmune and other diseases mediated by RORy study (WO2017132432A1; compound 2)[1].
Web ID
– HY-142940
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C27H22F5N3O6S
References
– [1]David A. Claremon, et al. Benzimidazole derivatives as modulators of ror-gamma. WO2017132432A1.
CAS Number
– 2119042-65-6
Molecular Weight
– 611.54
SMILES
– FC(F)(F)C1=NC2=CC(C(N[C@H](C3=CC=C(C=C3)S(CC)(=O)=O)CO)=O)=CC=C2N1CC4=C5C(OC(F)(O5)F)=CC=C4
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– ROR
Isoform
– RORγ
Pathway
– Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
