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RLX-33
Price range: 120 CAD through 2,848 CAD
Products Details
Product Description
– RLX-33 is a potent and selective antagonist of relaxin family peptide 3 (RXFP3) that crosses the blood-brain barrier and also blocks relaxin 3-induced ERK1/2 phosphorylation. RLX-33 can block the increase in food intake induced by the RXFP3 selective agonist R3/I5 in rats.RLX-33 can be used to study the metabolic syndrome.
Web ID
– T62929
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H19ClN4O4
References
– Gay EA, Guan D, Van Voorhies K, Vasukuttan V, Mathews KM, Besheer J, Jin C. Discovery and Characterization of the First Nonpeptide Antagonists for the Relaxin-3/RXFP3 System. J Med Chem. 2022 Jun 9;65(11):7959-7974. doi: 10.1021/acs.jmedchem.2c00508. Epub 2022 May 20. PMID: 35594150; PMCID: PMC9255433.
CAS Number
– 2784577-71-3
Molecular Weight
– C24H19ClN4O4
Compound Purity
– 0.9982
SMILES
– N(C(=O)C1CN(CC2=CC=CO2)C(=O)C1)C3=CC=C(C4=NC(=NO4)C5=CC=C(Cl)C=C5)C=C3
Pathway
– MAPK|||GPCR/G Protein
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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