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Risdiplam
SKU
HY-109101-10 mg
Category Reference compound
Tags Cell Cycle/DNA Damage, DNA/RNA Synthesis, Neurological Disease
$165 – $1,485
Products Details
Product Description
– Risdiplam (RG7916) is an orally administered, centrally and peripherally distributed SMN2 pre-mRNA splicing modifier that increases survival motor neuron (SMN) protein levels[1].
Web ID
– HY-109101
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C22H23N7O
References
– [1]Poirier A, et al. Risdiplam distributes and increases SMN protein in both the central nervous system and peripheral organs. Pharmacol Res Perspect. 2018 Nov 29;6(6):e00447.
CAS Number
– 1825352-65-5
Molecular Weight
– 401.46
Compound Purity
– 99.58
SMILES
– O=C(C=C(C(C=C1C)=NN2C1=NC(C)=C2)N=C3C=C4)N3C=C4N(CCN5)CC65CC6
Clinical Information
– Launched
Research Area
– Neurological Disease
Solubility
– DMSO : 1.7 mg/mL (ultrasonic;warming;heat to 60°C)|Ethanol : < 1 mg/mL|H2O : < 0.1 mg/mL
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.