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Products Details
Product Description
– RIP1 kinase inhibitor 5 (example 1) is a potent inhibitor of RIP1, which is used as a checkpoint kinase to control tumor immunity[1]. RIP1 kinase inhibitor 5 is similar with SIR1-365 (compound 13), which inhibits necrosis and iron death activity[2].
Web ID
– HY-153435
Shipping
– Room temperature
Molecular Formula
– C13H17F2NO2
References
– [1]Su Yaning, et al. Preparation of cyrstalline forms of RIP1 inhibitor. World Intellectual Property Organization, WO2023066368 A1. 2023-04-27. |[2]Su Yaning, et al. Preparation of substituted amides as RIP1 inhibitors. World Intellectual Property Organization, WO2020103859 A1. 2020-05-28.
CAS Number
– 2428422-17-5
Molecular Weight
– 257.28
SMILES
– CCC(C)(C)C(N(CC1=CC(F)=CC(F)=C1)O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Necroptosis;RIP kinase
Pathway
– Apoptosis
Product type
– Reference compound
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