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RBPJ Inhibitor-1
SKU
HY-137471-10 mg
Category Reference compound
Tags Cancer, Neuronal Signaling;Stem Cell/Wnt, Notch
$100 – $980
Products Details
Product Description
– RBPJ Inhibitor-1 (RIN1), the first RBPJ inhibitor, blocks the functional interaction of RBPJ with SHARP. RBPJ Inhibitor-1 (RIN1) inhibits NOTCH-dependent tumor cell proliferation[1].
Web ID
– HY-137471
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C17H14FN3O2
References
– [1]Cecilia Hurtado, et al. Disruption of NOTCH signaling by a small molecule inhibitor of the transcription factor RBPJ. Sci Rep. 2019 Jul 25;9(1):10811.
CAS Number
– 2682114-39-0
Molecular Weight
– 311.31
Compound Purity
– 99.80
SMILES
– O=C(N)C1=CC=C(C2=CC=NN2C)C=C1OC3=CC=CC=C3F
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Notch
Pathway
– Neuronal Signaling;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.