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Raloxifene
$70 – $240
Products Details
Product Description
– Raloxifene (Keoxifene) is a benzothiophene-derived selective estrogen receptor modulator (SERM). Raloxifene has estrogen-agonistic effects on bone and lipids and estrogen-antagonistic effects on the breast and uterus. Raloxifene is used for breast cancer and osteoporosis research[1].
Web ID
– HY-13738
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C28H27NO4S
Citations
– ACS Omega. 2023 Jun 14.|J Pharmaceut Biomed. 2020, 113870.|Eberhard Karls Universität Tübingen. 2021 Aug.|Free Radic Biol Med. 2017 Apr 10;108:404-417.|Med Sci Monit. 2019 Apr 29;25:3146-3153.|Oxid Med Cell Longev. 2021 Mar 20;2021:6699054.|PLoS Negl Trop Dis. 2019 Aug 20;13(8):e0007681. |Research Square Preprint. 2020 Nov 4;rs.3.rs-100914.|Viruses. 2021 Jun 28;13(7):1255.
References
– [1]Khovidhunkit W, et al. Clinical effects of raloxifene hydrochloride in women. Ann Intern Med. 1999;130(5):431-439.|[2]Xu H, et al. Effect of caffeine on ovariectomy-induced osteoporosis in rats. Biomed Pharmacother. 2019;112:108650.
CAS Number
– 84449-90-1
Molecular Weight
– 473.58
Compound Purity
– 99.62
SMILES
– O=C(C1=C(C2=CC=C(O)C=C2)SC3=CC(O)=CC=C31)C4=CC=C(OCCN5CCCCC5)C=C4
Clinical Information
– Launched
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Estrogen Receptor/ERR
Isoform
– Estrogen receptor
Pathway
– Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
