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Products Details
Product Description
– (R)-Pomalidomide-pyrrolidine, a CRBN ligand, can be connected to the ligand for protein by a linker to form PROTACs.
Web ID
– HY-132944
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C17H18N4O4
References
– [1]Sun D, et al. Evaluation of the Small-molecule BRD4 Degrader CFT-2718 in Small-cell Lung Cancer and Pancreatic Cancer Models. Mol Cancer Ther. 2021 Aug;20(8):1367-1377.
CAS Number
– 2418618-52-5
Molecular Weight
– 342.35
SMILES
– O=C(N1C2C(NC(CC2)=O)=O)C3=CC=CC(N[C@@H]4CCNC4)=C3C1=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ligands for E3 Ligase
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
