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Products Details
Product Description
– (R)-MIK665 is the less active enantiomer of MIK665. MIK665 is a special Mcl-1 inhibitor with an IC50 of 1.81 nM.
Web ID
– HY-112218A
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C47H44ClFN6O6S
References
– [1]Andras Kotschy, et al. New thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them. EP2886545A1.
CAS Number
– 1799831-02-9
Molecular Weight
– 875.41
SMILES
– OC([C@@H](CC(C=CC=C1)=C1OCC2=CC=NC(C3=CC=CC=C3OC)=N2)OC4=C5[C@@]([C@@]6=C(C)C(Cl)=C(OCCN7CCN(C)CC7)C=C6)=C(C8=CC=C(F)C=C8)SC5=NC=N4)=O.[R].[R]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Bcl-2 Family
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
