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Products Details
Product Description
– (R)-GSK-3685032 is the R-enantiomer of GSK-3685032, a first-in-class, non-time-dependent, non-covalent, reversible, selective DNMT1 inhibitor with an IC50 of 0.036 μM, which induces robust loss of DNA methylation, transcriptional activation, and inhibition of cancer cell growth.
Web ID
– T39648
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C22H24N6OS
References
– Adams, Nicholas David, et al. Substituted pyridines as inhibitors of DNMT1 and their preparation. WO2017216727A1.
CAS Number
– 2170140-50-6
Molecular Weight
– C22H24N6OS
SMILES
– CCc1c(C#N)c(S[C@@H](C(N)=O)c2ccccc2)nc(N2CCC(N)CC2)c1C#N
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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