(R)-Atuveciclib

SKU T10464-100 mg Category Brand:

2,416 CAD

Only 1000 item(s) left in stock.

Products Details

Product Description

– (R)-Atuveciclib is an isomer of Atuveciclib. Atuveciclib (BAY 1143572) is a potent and highly selective PTEFb/CDK9 inhibitor with an IC50 value of 13 nm for CDK9/CycT1 and a selectivity ratio of 100 for CDK2, with highly bioavailable and orally available advantages.

Web ID

– T10464

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H18FN5O2S

References

– Lücking U, et al. Identification of Atuveciclib (BAY 1143572), the First Highly Selective, Clinical PTEFb/CDK9 Inhibitor for the Treatment of Cancer. ChemMedChem. 2017 Nov 8;12(21):1776-1793.

CAS Number

– 2923012-24-0

Molecular Weight

– C18H18FN5O2S

SMILES

– O(C)C1=C(C=CC(F)=C1)C=2N=C(NC3=CC(CS(C)(=N)=O)=CC=C3)N=CN2

Target

– Others

Pathway

– Cell Cycle/Checkpoint

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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