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Protein kinase inhibitor 5
SKU
HY-153745-Get quote
Category Reference compound
Tags Cancer, Neuronal Signaling;Protein Tyrosine Kinase/RTK, Trk Receptor
Products Details
Product Description
– Protein kinase inhibitor 5 is a potent TRK-A inhibitor with an IC50 value of 1.8 nM. Protein kinase inhibitor 5 inhibits cell viability[1].
Web ID
– HY-153745
Shipping
– Room temperature
Molecular Formula
– C29H31F2N7O
References
– [1]Dawei Zhang, et al. Substituted pyrazolopyrimidines useful as kinases inhibitors. WO2019029629A1.
CAS Number
– 2278204-94-5
Molecular Weight
– 531.60
SMILES
– O=C(NC1=C2N=C(N3[C@@H](C4=CC(F)=CC=C4F)CCC3)C=CN2N=C1)C5=CC=C(CN6CCN(C)CC6)C=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Trk Receptor
Isoform
– TrkA
Pathway
– Neuronal Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.