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Products Details
Product Description
– PROTACSMARCA2 degrader-4 (Compound I-424) is a PROTAC degradative agent targeting the catalytic subunits SMARCA2 and SMARCA4 of the SWI/SNF complex. It effectively degrades SMARCA2 in MV411 and A549 cell lines with a DC50 of less than 100 nM and degrades SMARCA4 in MV411 with a DC50 exceeding 1 μM.
Web ID
– T89436
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C55H68N12O5S
CAS Number
– 2568523-70-4
Molecular Weight
– C55H68N12O5S
SMILES
– O=C(NCC=1C=CC(=CC1)C=2SC=NC2C)C3N(C(=O)C(NC(=O)C4CC5(C4)CC(N6CCC(C7=CN=C(N=C7)N8C9CN(C=%10C=C(N=NC%10N)C%11=CC=CC=C%11O)CC8CC9)CC6)C5)C(C)(C)C)CC(O)C3
Product type
– PROTAC
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